Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC610H961N161O181S13

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKAGWFVQRCWKNDIGYCRKRCFLIERYKLLCMNKLSCCIPLSSDDPYTQWPIQPPSLEDVTAEFVTQDDIPFTPGSGMDDSVTIEMTQESTAIRPRSSQRHSS
    

Molecular Weight13862.97 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-1.47

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0121

GRAVY Index-0.15

Hydrophobic Moment 0.59

Boman Index0.02

Instability Index49.28

Aliphatic Index 78.93

Aromaticity 0.0909

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5482.68

LogP -52.18

H-bond Donors 197.0

H-bond Acceptors 194.0

Rotatable Bonds 451.0

Heavy Atoms 965.0

Ring Count 23.0

Amide Bonds 129.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0289388 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyDefensin

Tax ID9925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence