Peptide Database

Peptide NameMu-conotoxin TsIIIA

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC78H127N29O23S7

DescriptionStandard

        GCCRWPCPSRCGMARCCSS
    

Molecular Weight2063.48 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.1421

GRAVY Index-0.11

Hydrophobic Moment 0.28

Boman Index-0.16

Instability Index82.69

Aliphatic Index 5.26

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 831.72

LogP -12.76

H-bond Donors 37.0

H-bond Acceptors 33.0

Rotatable Bonds 61.0

Heavy Atoms 137.0

Ring Count 4.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217107 VERIFIED: NO

Provenance & Taxonomy

OrganismConus tessulatus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-11; 3-16; 7-17

Bio-Activity Profile

Function

Toxin Ion channel blocker