Peptide Database

Peptide NameTP1[W2A]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC91H149N33O20S4

DescriptionStandard

        KACFRVCYRGICYRRCR
    

Molecular Weight2153.63 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 5.45

Charge Density (pH 7.0) 0.3363

GRAVY Index-0.36

Hydrophobic Moment 0.66

Boman Index-0.45

Instability Index39.07

Aliphatic Index 45.88

Aromaticity 0.1765

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 904.90

LogP -8.19

H-bond Donors 40.0

H-bond Acceptors 30.0

Rotatable Bonds 70.0

Heavy Atoms 148.0

Ring Count 3.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426954 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetAcinetobacter baumannii ATCC 19606

Activity0.5 μg/mL

MethodMIC

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