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MYP_066683
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Basic Information
Triintsin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
38 amino acids
C174H275N55O52S6
Standard
Sequence
GFGCPLNERECHSHCQSIGRKFGYCGGTLRLTCICGKE
Physicochemical Analysis
4161.77 Da
8.34
1.89
1.48
0.0496
-0.34
0.55
-0.05
46.14
51.32
0.0789
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1725.56
-21.03
67.0
62.0
138.0
287.0
6.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132159 VERIFIED: YES
Provenance & Taxonomy
Trichophyton interdigitale [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis AB91021
0.25 μM
MIC
PMID30102941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30102941/
RECORD: Rec_0142186 VERIFIED: YES
Provenance & Taxonomy
Trichophyton interdigitale [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
0.25 μM
MIC
PMID30102941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30102941/
RECORD: Rec_0146911 VERIFIED: YES
Provenance & Taxonomy
Trichophyton interdigitale [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD analysis reveals that the sequence of the peptide shows 73.7% similarity to Micasin-1 Mol Wt: 4161.831; GRAVY: -0.339; mol formula: C174H276N54O52S6. 18% G, 15%C. Chemical modification: Three disulfide bonds: Cys4-Cys25, Cys11-Cys33, and Cys15-Cys35
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus epidermidis AB208187 or AB208188
4-8 μM
MIC
PaperTriintsin, a human pathogenic fungus-derived defensin with broad-spectrum antimicrobial activity.
RECORD: Rec_0158644 VERIFIED: YES
Provenance & Taxonomy
Trichophyton interdigitale [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD analysis reveals that the sequence of the peptide shows 73.7% similarity to Micasin-1 Mol Wt: 4161.831; GRAVY: -0.339; mol formula: C174H276N54O52S6. 18% G, 15%C. Chemical modification: Three disulfide bonds: Cys4-Cys25, Cys11-Cys33, and Cys15-Cys35
Bio-Activity Profile
Antimicrobial Antifungal
G- Escherichia coli AB94012 or ATCC 25922
0.06-0.25 μM
MIC
PaperTriintsin, a human pathogenic fungus-derived defensin with broad-spectrum antimicrobial activity.
RECORD: Rec_0178957 VERIFIED: NO
Provenance & Taxonomy
Trichophyton tonsurans [Fungus]; Trichophyton interdigitale [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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