Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC342H525N83O93S9

DescriptionStandard

        MKLLFVMLALLFFWDPALAGLNPLAAEIHNKCYRNGICRLECYTSEMLVDYCEFQLECCVKGNPDP
    

Molecular Weight7575.91 Da

Isoelectric Point (pI)4.79

Net Charge (pH 7.0)-3.46

Net Charge (pH 7.4) -3.83

Charge Density (pH 7.0) -0.0524

GRAVY Index0.32

Hydrophobic Moment 0.56

Boman Index0.18

Instability Index25.69

Aliphatic Index 97.58

Aromaticity 0.1212

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2780.99

LogP -16.36

H-bond Donors 98.0

H-bond Acceptors 100.0

Rotatable Bonds 243.0

Heavy Atoms 527.0

Ring Count 14.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188067 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence