Peptide Database

Peptide NameMotilin

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC125H200N38O36

DescriptionStandard

        FVPIFTYSELRRTQEREQNKRL
    

Molecular Weight2811.16 Da

Isoelectric Point (pI)9.97

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.0803

GRAVY Index-1.19

Hydrophobic Moment 0.50

Boman Index-0.42

Instability Index101.51

Aliphatic Index 66.36

Aromaticity 0.1364

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1261.34

LogP -11.75

H-bond Donors 45.0

H-bond Acceptors 38.0

Rotatable Bonds 95.0

Heavy Atoms 199.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031357 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyMotilin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0051543 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0243052 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0287263 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyMotilin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Gastrointestinal