Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC438H702N142O133S7

DescriptionStandard

        MRTLALFAAAVLLVVLQAQAEPLQARDDEVAAQEQLGADAQEASVSFVWDEGASHQLSGSGRGSGCICRRGRCRFGERQAGTCLFRGRAYRFCCR
    

Molecular Weight10309.59 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.55

Net Charge (pH 7.4) 1.18

Charge Density (pH 7.0) 0.0163

GRAVY Index-0.13

Hydrophobic Moment 0.65

Boman Index-0.06

Instability Index25.33

Aliphatic Index 75.16

Aromaticity 0.0737

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4476.99

LogP -53.25

H-bond Donors 166.0

H-bond Acceptors 143.0

Rotatable Bonds 345.0

Heavy Atoms 720.0

Ring Count 10.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164632 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence