Peptide Database

Peptide NameBasic phospholipase A2 myotoxin I (MT-I) (svPLA2) (EC 3.1.1.4) (Myotoxic phospholipase) (Myotoxin III) (Phosphatidylcholine 2-acylhydrolase)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC694H1087N185O197S18

DescriptionStandard

        MRTLWIMAVLLVGVEGSLIEFAKMILEETKRLPFPYYTTYGCYCGWGGQGQPKDATDRCCFVHDCCYGKLSNCKPKTDRYSYSRKSGVIICGEGTPCEKQICECDKAAAVCFRENLRTYKKRYMAYPDLLCKKPAEKC
    

Molecular Weight15751.35 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)6.46

Net Charge (pH 7.4) 5.93

Charge Density (pH 7.0) 0.0468

GRAVY Index-0.33

Hydrophobic Moment 0.68

Boman Index-0.05

Instability Index38.94

Aliphatic Index 63.62

Aromaticity 0.1159

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26775.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6148.47

LogP -53.87

H-bond Donors 230.0

H-bond Acceptors 223.0

Rotatable Bonds 519.0

Heavy Atoms 1094.0

Ring Count 26.0

Amide Bonds 142.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396728 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops asper [Animal]

FamilyPhospholipase A2; Group II subfamily; D49 sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Hydrolase Toxin Cytotoxic Non-hemolytic

TargetNo Target Organism Found