Peptide Database

Peptide NameSerine protease inhibitor Kazal-type 1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC283H449N85O87S7

DescriptionStandard

        GNPPAEVNGKTPNCPKQIMGCPRIYDPVCGTNGITYPSECSLCFENRKFGTSIHIQRRGTC
    

Molecular Weight6658.56 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0458

GRAVY Index-0.57

Hydrophobic Moment 0.50

Boman Index-0.07

Instability Index48.22

Aliphatic Index 49.51

Aromaticity 0.0656

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2755.26

LogP -34.96

H-bond Donors 98.0

H-bond Acceptors 98.0

Rotatable Bonds 210.0

Heavy Atoms 462.0

Ring Count 12.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193489 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilySerine protease inhibitor Kazal-type

Tax ID10116

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide14-43; 21-40; 29-61

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour