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MYP_066596
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C28H45N7O6
Standard
Sequence
HLPLP
Physicochemical Analysis
575.70 Da
6.74
-0.15
-0.41
-0.0305
0.24
0.04
0.39
85.04
156.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
190.82
0.41
5.0
7.0
13.0
41.0
3.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011802 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 20.0%, C 80.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0027313 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]; Gallus gallus [Animal]
9913; 9606; 9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAntihypertensive peptides from food proteins: a review PMID22249830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22249830/
RECORD: Rec_0035414 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-Casein-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
21.6 μM
IC50
PaperChanges in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats | Miguel, M. et al. | DOI: 10.1002/mnfr.200900449 Evidence URLhttps://www.uniprot.org/uniprotkb/P05814/entry
RECORD: Rec_0036578 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
ACE-inhibitory peptide
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperPrimary and secondary structure of novel ACE-inhibitory peptides from egg white protein
RECORD: Rec_0042352 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal] [Animal]; Bos taurus [Animal]
Casein-derived peptide
9606;9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Antihypertensive Neuropeptide ACE inhibitory
Angiotensin-I converting enzyme
41 μM
IC50
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