Peptide Database

Peptide NameCathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC893H1483N263O258S6

DescriptionStandard

        MGARKDGASSGRLSLPLPLPLLLLLLLLQLLGSLPSPAATQALGYQEAVRQAVADFNKRSLDPSLFRLLSLDSTPSGDEDPGTPKPVSFTVKETVCPKATQLPLEQCDFKENGVVKRCTGTVTLGPASSASGVSCDRAQRVRRMVGLRKFLRKTGRKLRKTLQKIGNALQKFQPRPQFPSNYPNRV
    

Molecular Weight20224.33 Da

Isoelectric Point (pI)10.40

Net Charge (pH 7.0)15.47

Net Charge (pH 7.4) 15.16

Charge Density (pH 7.0) 0.0832

GRAVY Index-0.31

Hydrophobic Moment 0.92

Boman Index-0.08

Instability Index50.48

Aliphatic Index 88.60

Aromaticity 0.0484

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8387.06

LogP -110.47

H-bond Donors 293.0

H-bond Acceptors 280.0

Rotatable Bonds 671.0

Heavy Atoms 1420.0

Ring Count 26.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010776 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence