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MYP_066587
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor Of Cytosol Alanyl Aminopeptidase
Enzyme modulation ▸ Enzyme inhibition ▸ Lactocepin Inhibitor
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
2 amino acids
C12H24N2O3
Standard
Sequence
LL
Physicochemical Analysis
244.33 Da
5.53
-0.24
-0.44
-0.1200
3.80
0.68
1.06
5.00
390.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
92.42
0.98
3.0
3.0
7.0
17.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0183142 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
IC50
PaperStudies on purification and the molecular mechanism of a novel ACE inhibitory peptide from whey protein hydrolysate | Pan, D. et al. | DOI: 10.1016/j.foodchem.2011.07.011 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0183759 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 2-[(11aS)-1,3,4,11a-tetrahydro-6-oxo-2H-benzo[b]quinolizin-11(6H)-ylidene]-, (2Z)-acetic acid
Bio-Activity Profile
-
PaperAdvanced Synthesis & Catalysis Evidence URLhttps://doi.org/10.1002/1615-4169(200209
RECORD: Rec_0305767 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Amaranthus hypochondriacus [Plant]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Anti-inflammatory Taste
Angiotensin-converting enzyme
RECORD: Rec_0312111 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0364146 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Inhibitor Of Cytosol Alanyl Aminopeptidase
Cytosol alanyl aminopeptidase
PaperGarner C.W., Behal F. J.. Human liver alanine aminopeptidase. Inhibition by amino acids. Biochemistry, 14, 3208-3212, 1975.
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