Peptide Database

Peptide NameUperin 3.6 [D4K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC87H153N23O20

DescriptionStandard

        GVIKAAKKVVNVLKNLF
    

Molecular Weight1841.29 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2209

GRAVY Index0.72

Hydrophobic Moment 0.73

Boman Index0.19

Instability Index-5.57

Aliphatic Index 148.82

Aromaticity 0.0588

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 719.18

LogP -3.90

H-bond Donors 24.0

H-bond Acceptors 24.0

Rotatable Bonds 65.0

Heavy Atoms 130.0

Ring Count 1.0

Amide Bonds 18.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0111212 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans SC5314

Activity64 μg/mL

MethodMIC

RECORD: Rec_0208216 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida krusei ATCC 6258

Activity64 μg/mL

MethodMIC

RECORD: Rec_0273025 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity10 % hemolysis at >256 μg/mL

MethodHemolysis

RECORD: Rec_0344844 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans ATCC 90028

Activity128 μg/mL

MethodMIC

RECORD: Rec_0364290 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida parapsilosis ATCC 22019

Activity64 μg/mL

MethodMIC