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MYP_066536
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Basic Information
Orexin-B
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C126H214N44O35S
Standard
Sequence
RPGPPGLQGRLQRLLQANGNHAAGILTM
Physicochemical Analysis
2937.39 Da
12.00
2.85
2.59
0.1017
-0.39
0.56
-0.01
53.77
94.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1272.71
-15.06
42.0
40.0
95.0
206.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0273100 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]; Rattus norvegicus [Animal]
10090; 10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0313363 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0336040 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Orexin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator
PMID9491897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9491897/
RECORD: Rec_0409696 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 32.1%, C 17.9% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
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