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MYP_066536
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Basic Information
Orexin-B
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C126H214N44O35S
Standard
Sequence
RPGPPGLQGRLQRLLQANGNHAAGILTM
Physicochemical Analysis
2937.39 Da
12.00
2.85
2.59
0.1017
-0.39
0.56
-0.01
53.77
94.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1272.71
-15.06
42.0
40.0
95.0
206.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036772 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Orexin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Orexin-B (Rattus norvegicus): PMID 9491897 PMID9491897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9491897/
RECORD: Rec_0092790 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Orexin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator
PMID9491897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9491897/
RECORD: Rec_0116936 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Orexin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation Sleep regulation Wake regulation Feeding regulator
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Orexin-B (Rattus norvegicus): PMID 9491897 PMID9491897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9491897/
RECORD: Rec_0162817 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Orexin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
RECORD: Rec_0258366 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]; Mus musculus [Animal]
10116, 10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
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