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MYP_066457
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Basic Information
Hepcidin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Regulatory peptide ▸ Biological modulation
Standard
25 amino acids
C113H178N34O31S9
Standard
Sequence
DTHFPICIFCCGCCHRSKCGMCCKT
Physicochemical Analysis
2797.42 Da
8.22
1.85
1.43
0.0742
0.39
0.15
0.07
37.76
31.20
0.0800
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1022.22
-11.75
44.0
44.0
88.0
187.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011099 VERIFIED: NO
Provenance & Taxonomy
Gorilla gorilla [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID18321376 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18321376/
RECORD: Rec_0025083 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0039949 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Hepcidin
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
PaperPubMed PMID: 11034317 | PubMed PMID: 11113131 | PubMed PMID: 12138110 | PubMed PMID: 19553669 PMID11034317;11113131;12138110;19553669 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11034317/
RECORD: Rec_0042935 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Hepcidin
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
group B Streptococcus
PaperPubMed PMID: 11034317 | PubMed PMID: 11113131 | PubMed PMID: 12138110 | PubMed PMID: 19553669 PMID11034317;11113131;12138110;19553669 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11034317/
RECORD: Rec_0049040 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Bubalus bubalus [Animal]
Hepcidin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-13; 10-23; 11-22; 14-19
Bio-Activity Profile
Antimicrobial
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