Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length497 amino acids

Chemical FormulaC2439H3863N653O685S19

DescriptionStandard

        MARGPDNAPRWALLAVLAAVGTAMTAAINPGAVARISQKGLDYACQEGTAVLQKDLEKIKIPNYSRKFKIKVLGKGNYSFYSMNVRGFQLPSRQVILVPDVGLKLFIGNASVKISGKWKAQKSFIKTSGNFDLTVEGVSISAGVRVGSDPASGKATVTCSGCSSHISSVGVHIAGSRLGWLIRLFRKQIESSIRNNIQDKICKVVANSVSSKLQPFFQNLPVMAKIDAVAGIDYRLVAPPTATSEYLDGHLKGEFFSWADPMPPPFAPPALEFPAIHDRMVYLGLSEYFFNTAGLVYYEAGALQLTLTDDMIPEKSSFRLTTRFFGTFLPQVAQMFPDMNMQLDVSVSTPPHLSMQSSGLVLTPYLEAETFAILPNSSLASLFLLGLSTNASVRVGAMASRLVGELELDRLLLELKHSNIGPFPVALLQAIMDYAVPTLVLPRVNQKLQRGFPLPVPSHFQLYNPVLRSHQGVLLFGADVRHAEVAPSAGGCRRSCS
    

Molecular Weight53902.96 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)13.25

Net Charge (pH 7.4) 12.40

Charge Density (pH 7.0) 0.0267

GRAVY Index0.13

Hydrophobic Moment 0.76

Boman Index0.13

Instability Index39.85

Aliphatic Index 96.74

Aromaticity 0.0865

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41745.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0227714 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus (Gray mouse lemur) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria