Peptide Database

Peptide NameKABT (1-11)-Uperin 3.6 (11-17), KU2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC117H180N28O21

DescriptionStandard

        GIWKKWIKKWLNVLKNLF
    

Molecular Weight2314.86 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.2642

GRAVY Index-0.12

Hydrophobic Moment 0.77

Boman Index0.11

Instability Index2.15

Aliphatic Index 124.44

Aromaticity 0.2222

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 821.67

LogP 0.97

H-bond Donors 29.0

H-bond Acceptors 26.0

Rotatable Bonds 78.0

Heavy Atoms 166.0

Ring Count 7.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018845 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida parapsilosis ATCC 22019

Activity8 μg/mL

MethodMIC

RECORD: Rec_0177237 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans SC5314

Activity8 μg/mL

MethodMIC

RECORD: Rec_0269904 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans ATCC 90028

Activity16 μg/mL

MethodMIC

RECORD: Rec_0309478 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida krusei ATCC 6258

Activity16 μg/mL

MethodMIC

RECORD: Rec_0396985 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity10 % hemolysis at 7.33±0.73 μg/mL

MethodHemolysis