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MYP_066293
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Basic Information
Pseudhymenochirin-1Pb [E17k]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C148H256N40O35
Standard
Sequence
IKIPSFFRNILKKVGKKAVSLIAGALKQS
Physicochemical Analysis
3155.86 Da
11.43
6.75
6.54
0.2329
0.31
0.81
0.09
41.23
124.48
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1234.22
-8.92
43.0
42.0
112.0
223.0
3.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161031 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer
A549
2.1±0.7 μM
IC50
PaperPubMed PMID: 26606380 PMID26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26606380/
RECORD: Rec_0294249 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Mouse erythrocytes: ±4μM
50 %
Hemolysis
PaperPubMed PMID: 26606380 PMID26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26606380/
RECORD: Rec_0326423 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 26606380 PMID26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26606380/
RECORD: Rec_0343404 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
11±2 μM
IC50
PaperPubMed PMID: 26606380 PMID26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26606380/
RECORD: Rec_0349058 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
3.6±0.5 μM
IC50
PaperPubMed PMID: 26606380 PMID26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26606380/