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MYP_066290
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
17 amino acids
C99H154N32O20S4
Standard
Sequence
KWCFRVCYRGICYRKCR
Physicochemical Analysis
2240.74 Da
9.79
5.72
5.45
0.3363
-0.48
0.65
-0.38
-20.47
40.00
0.2353
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
884.81
-5.62
39.0
30.0
72.0
155.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0296418 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
86.4±12.2 μM
HC50
PMID31455019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31455019/
RECORD: Rec_0321235 VERIFIED: NO
Provenance & Taxonomy
Tachypleus gigas [Animal]; Carcinoscorpius rotundicauda [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
3-16; 7-12
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0326358 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
0.25
MIC
PMID31455019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31455019/
RECORD: Rec_0349889 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis B-886
1 μM
MIC
PMID30486233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30486233/
RECORD: Rec_0352442 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Tachyplesin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Pseudomonas aeruginosa ATCC 27853
4.466 μM
Total countable CFUs
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