Peptide Database

Peptide NameGlucagon-like peptide 1B

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC165H249N39O52

DescriptionStandard

        HAEGTYTNDVTEYLEEKAAKEFIEWLIKGKP
    

Molecular Weight3610.97 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-3.14

Net Charge (pH 7.4) -3.41

Charge Density (pH 7.0) -0.1013

GRAVY Index-0.83

Hydrophobic Moment 0.64

Boman Index-0.04

Instability Index16.00

Aliphatic Index 69.35

Aromaticity 0.1290

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1481.42

LogP -10.36

H-bond Donors 50.0

H-bond Acceptors 50.0

Rotatable Bonds 120.0

Heavy Atoms 256.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117782 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyGlucagon

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0128203 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0406761 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyGlucagon-like peptide 1B

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour