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MYP_066281
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Basic Information
I7R
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
8 amino acids
C68H89N21O9
Standard
Sequence
WWWLRRRW
Physicochemical Analysis
1344.57 Da
12.00
2.76
2.56
0.3450
-1.66
0.38
-0.41
263.05
48.75
0.5000
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.88
1.52
22.0
12.0
37.0
98.0
8.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302413 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
50%; R: 38%; L:13%. Mol. Wt: 1344.591; GRAVY: -1.66; Mol. ex. coeff.: 22200
Bio-Activity Profile
Antimicrobial Antifungal
Acinetobacter baumannii B28-16
32 μM
MIC
Unspecified 48 h
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0304855 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
50%; R: 38%; L:13%. Mol. Wt: 1344.591; GRAVY: -1.66; Mol. ex. coeff.: 22200
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli E423-17
16-32 μM
MIC
Unspecified 48 h
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0331788 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
50%; R: 38%; L:13%. Mol. Wt: 1344.591; GRAVY: -1.66; Mol. ex. coeff.: 22200
Bio-Activity Profile
Antimicrobial Antifungal
K-pneumoniae E406-17
>32 μM
MIC
Unspecified 48 h
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0344818 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
50%; R: 38%; L:13%. Mol. Wt: 1344.591; GRAVY: -1.66; Mol. ex. coeff.: 22200
Bio-Activity Profile
Antimicrobial Antifungal
P-aeruginosa E411-17
>32 μM
MIC
Unspecified 48 h
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0355787 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2019/0048052 A1 Evidence URLhttps://patents.google.com/patent/US20190048052A1/en PatentUS 2019/0048052 A1
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