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MYP_066276
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Basic Information
Gramicidin S analog 11
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
PXXXXXFPXXXLXF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0135006 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus N229-T034-PVL-
8.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0148823 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0195415 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,4,5,6,9,10,11,13
Bio-Activity Profile
Hemolytic
human red blood cells
100 % hemolysis at 15.6 μM
Hemolysis
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0253253 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 49775
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0287615 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,3,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus USA 300-1110301146 PVL+
8.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
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