Peptide Database

Peptide NameAntimicrobial peptide TsAP-2 (Non-disulfide-bridged peptide 4.23) (NDBP-4.23)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC384H623N105O99S3

DescriptionStandard

        MQIKHLITIFFLVLIVADHCHAFLGMIPGLIGGLISAFKGRRKREITSQIEQYRNLQKREAELENLLANLPVY
    

Molecular Weight8390.89 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.0378

GRAVY Index0.24

Hydrophobic Moment 0.50

Boman Index0.13

Instability Index45.64

Aliphatic Index 125.62

Aromaticity 0.0822

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3287.37

LogP -21.27

H-bond Donors 114.0

H-bond Acceptors 108.0

Rotatable Bonds 286.0

Heavy Atoms 591.0

Ring Count 11.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106928 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetCryptococcus neoformans

RECORD: Rec_0267403 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0270601 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetCandida spp.

RECORD: Rec_0311053 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetCandida albicans

RECORD: Rec_0373191 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetEnterococcus faecalis