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MYP_066259
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Basic Information
Pb-CATH3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
22 amino acids
C125H202N44O24S
Standard
Sequence
HRVKRNGFRKFMRRLKKFFAGG
Physicochemical Analysis
2737.29 Da
12.00
8.84
8.58
0.4020
-1.05
1.00
-0.47
46.19
35.45
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.77
-9.41
44.0
35.0
97.0
194.0
5.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0205826 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
3 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0207827 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
chicken red blood cells
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0229547 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
3 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity.
RECORD: Rec_0235408 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
128 μg/mL
MIC
PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0247902 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
8 μg/mL
MIC
PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
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