Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length139 amino acids

Chemical FormulaC680H1081N185O219S12

DescriptionStandard

        STGSFEPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISYEYTRRPPFRVIHLEDITFDYSDMGSFTGSPVSKLSDLVTFDTRGETMTPKTNTPETSMPPSETITSKTTMPSSETTTSKTTMPPPSQMALTHN
    

Molecular Weight15736.75 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.59

Net Charge (pH 7.4) 1.16

Charge Density (pH 7.0) 0.0115

GRAVY Index-0.57

Hydrophobic Moment 0.60

Boman Index-0.09

Instability Index70.15

Aliphatic Index 54.68

Aromaticity 0.0791

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6499.98

LogP -78.79

H-bond Donors 236.0

H-bond Acceptors 235.0

Rotatable Bonds 507.0

Heavy Atoms 1096.0

Ring Count 26.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163521 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0337258 VERIFIED: NO