Peptide Database

Peptide NameSenegalin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC375H613N103O119S3

DescriptionStandard

        MLSLKKSMLLLFFLGMVSFSLANKRSDGKRADEEGEDKRADEEGEDKRADEEGEDKRKRFLPFLIPALTSLISSLG
    

Molecular Weight8564.69 Da

Isoelectric Point (pI)5.16

Net Charge (pH 7.0)-2.47

Net Charge (pH 7.4) -2.72

Charge Density (pH 7.0) -0.0326

GRAVY Index-0.56

Hydrophobic Moment 0.52

Boman Index-0.15

Instability Index62.82

Aliphatic Index 82.24

Aromaticity 0.0658

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3629.76

LogP -34.65

H-bond Donors 127.0

H-bond Acceptors 120.0

Rotatable Bonds 305.0

Heavy Atoms 600.0

Ring Count 7.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168712 VERIFIED: YES

Provenance & Taxonomy

OrganismKassina senegalensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0253555 VERIFIED: YES

Provenance & Taxonomy

OrganismKassina senegalensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans

RECORD: Rec_0311484 VERIFIED: YES

Provenance & Taxonomy

OrganismKassina senegalensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)