Peptide Database

Peptide NamePore-forming peptide ameobapore A (EH-APP)

Function Ontology

Antimicrobial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC472H776N118O136S7

DescriptionStandard

        MKAIVFVLIFAVAFAVTATHQGEILCNLCTGLINTLENLLTTKGADKVKDYISSLCNKASGFIATLCTKVLDFGIDKLIQLIEDKVDANAICAKIHAC
    

Molecular Weight10504.37 Da

Isoelectric Point (pI)6.69

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.81

Charge Density (pH 7.0) -0.0039

GRAVY Index0.70

Hydrophobic Moment 0.68

Boman Index0.26

Instability Index19.83

Aliphatic Index 124.49

Aromaticity 0.0612

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4057.65

LogP -33.57

H-bond Donors 144.0

H-bond Acceptors 145.0

Rotatable Bonds 357.0

Heavy Atoms 733.0

Ring Count 8.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073074 VERIFIED: YES

Provenance & Taxonomy

OrganismEntamoeba histolytica [Protist]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Cytolytic Non-hemolytic