Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC165H273N51O54S2

DescriptionStandard

        KCNTATCVTQRLANFLVRSGNNLGAILSPTNVGSNTY
    

Molecular Weight3899.37 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0740

GRAVY Index-0.05

Hydrophobic Moment 0.72

Boman Index0.04

Instability Index12.72

Aliphatic Index 84.32

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1735.65

LogP -25.39

H-bond Donors 62.0

H-bond Acceptors 59.0

Rotatable Bonds 126.0

Heavy Atoms 272.0

Ring Count 3.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283829 VERIFIED: YES

Provenance & Taxonomy

OrganismDasypus novemcinctus [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)