Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC458H726N128O133S8

DescriptionStandard

        MRTLVILAAILLVALQAQAEPLQARTDEATAAQEQIPTDNPEVVVSLAWDESLAPRDSGLRKNMACYCRIPACFAGERRYGTCFYLGRVWAFCC
    

Molecular Weight10409.96 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0164

GRAVY Index0.16

Hydrophobic Moment 0.53

Boman Index0.07

Instability Index51.86

Aliphatic Index 92.55

Aromaticity 0.0851

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4175.63

LogP -38.19

H-bond Donors 151.0

H-bond Acceptors 140.0

Rotatable Bonds 333.0

Heavy Atoms 727.0

Ring Count 15.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208245 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence