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MYP_066145
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Basic Information
Antimicrobial peptide CHP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
39 amino acids
C196H321N59O49S6
Standard
Sequence
GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR
Physicochemical Analysis
4480.40 Da
9.90
8.70
8.40
0.2230
-0.05
0.54
-0.16
36.92
62.56
0.1282
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1778.84
-18.21
73.0
64.0
152.0
310.0
6.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002688 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-positive Non-hemolytic Non-ribosomal
Staphylococcus aureus
Qualitative functional evidence
PMID7964174 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7964174/; https://www.uniprot.org/uniprotkb/P80389/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0003402 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds: 6,28; 13,34; 18,35;
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
8 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0024835 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperEvans E.W., Beach G.G., Wunderlich J., Harmon B.G.;. "Isolation of antimicrobial peptides from avian heterophils.";J. Leukoc. Biol. 56:661-665. Evidence URLhttps://www.uniprot.org/uniprotkb/AMP1_CHICK/entry
RECORD: Rec_0081600 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds: 6,28; 13,34; 18,35;
Bio-Activity Profile
Antimicrobial Antifungal
P-multocida
>16 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0117302 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds: 6,28; 13,34; 18,35;
Bio-Activity Profile
Antimicrobial Antifungal
S. typhimurium
4 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
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