‹ ›
MYP_066127
← PREVIOUS NEXT → BACK
Basic Information
Dermaseptin-S1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor cross
Reproductive biology ▸ Contraceptive activity ▸ Spermicidal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C152H257N43O44S2
Standard
Sequence
ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Physicochemical Analysis
3455.06 Da
10.00
2.88
2.63
0.0847
0.19
0.51
0.18
1.85
92.35
0.0294
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1396.80
-14.41
49.0
50.0
118.0
241.0
3.0
35.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0276323 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Antiparasitic Spermicidal
Saccharomyces cerevisiae IP118079
5 μM
MIC
PaperIsolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin
RECORD: Rec_0277521 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagei [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiprotozoal
Escherichia coli (IP 76-24)
5 μg/mL
MIC
PMID1909573;8306981 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1909573/
RECORD: Rec_0300803 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagei [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiprotozoal
Aerornonas caviae IP (67-16) T
50 μg/mL
MIC
PMID1909573;8306981 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1909573/
RECORD: Rec_0300858 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/8306981/ PMID8306981 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8306981/
RECORD: Rec_0315526 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
70 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/7989335/ PMID7989335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7989335/
FIRST PREV 1 ... 6 7 8 9 10 ... 12 NEXT LAST
Showing 5 records on this page · Page 8 of 12