Peptide Database

Peptide NameDefensin alpha 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC468H735N135O157S8

DescriptionStandard

        MRTLTFLAAVLLVALQAQAEPLQAEDEPLQASAYEADAQEQRGEDNQDFTISFAADANSRIRALGSTRSFTCNCRRSCYSTEYSYGTCTVMGVSNRFCCL
    

Molecular Weight11021.17 Da

Isoelectric Point (pI)4.61

Net Charge (pH 7.0)-4.54

Net Charge (pH 7.4) -4.86

Charge Density (pH 7.0) -0.0454

GRAVY Index-0.21

Hydrophobic Moment 0.57

Boman Index-0.04

Instability Index52.91

Aliphatic Index 68.50

Aromaticity 0.0900

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4768.26

LogP -59.70

H-bond Donors 173.0

H-bond Acceptors 161.0

Rotatable Bonds 362.0

Heavy Atoms 768.0

Ring Count 11.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260638 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Tax ID9565

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal