Peptide Database

Peptide NameSLAY-screened peptide P2883

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC68H108N22O21S

DescriptionStandard

        CTHAHQRAISTYTI
    

Molecular Weight1601.78 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)0.92

Net Charge (pH 7.4) 0.60

Charge Density (pH 7.0) 0.0660

GRAVY Index-0.25

Hydrophobic Moment 0.38

Boman Index0.00

Instability Index20.44

Aliphatic Index 70.00

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 705.12

LogP -8.69

H-bond Donors 27.0

H-bond Acceptors 25.0

Rotatable Bonds 49.0

Heavy Atoms 112.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0315659 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/