Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC624H980N162O172S11

DescriptionStandard

        MKILLFFSISFFFDVFIPPVGSRSVGISVPPSKVPCLLKLEKLYSETRNSSTIFENAQYGTEEKQKAESKKHYALFNLTRACIMFGGHCKNKCGENEFRMVYCDVSTSLCCIRQCKPKKYK
    

Molecular Weight13856.15 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)8.60

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.0711

GRAVY Index-0.18

Hydrophobic Moment 0.57

Boman Index-0.01

Instability Index45.32

Aliphatic Index 71.65

Aromaticity 0.1240

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5396.50

LogP -48.42

H-bond Donors 195.0

H-bond Acceptors 194.0

Rotatable Bonds 465.0

Heavy Atoms 969.0

Ring Count 23.0

Amide Bonds 128.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174404 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyDefensin

Tax ID9925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence