Peptide Database

Peptide Namehuman defensin 5

Function Ontology

—

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC150H242N50O45S6

DescriptionStandard

        STCYCRSGLCAAIESYSGRCYISGRRYRLCCR
    

Molecular Weight3658.22 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)4.40

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.1375

GRAVY Index-0.20

Hydrophobic Moment 0.46

Boman Index-0.20

Instability Index53.43

Aliphatic Index 55.00

Aromaticity 0.1250

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1576.42

LogP -20.30

H-bond Donors 68.0

H-bond Acceptors 56.0

Rotatable Bonds 118.0

Heavy Atoms 251.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0126573 VERIFIED: YES

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)