‹ ›
MYP_066014
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
35 amino acids
C175H284N48O44S
Standard
Sequence
GFGSLFKFLAKKVAKTVAKQAAKQGAKYVANKHME
Physicochemical Analysis
3796.49 Da
10.30
6.85
6.57
0.1956
-0.27
0.69
-0.01
20.84
67.14
0.1143
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1516.82
-12.95
52.0
53.0
134.0
268.0
5.0
37.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0003370 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 77.1%, E 0.0%, T 11.4%, C 11.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Cytotoxic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0047545 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0050793 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal
PaperJ Biol Chem. 2002 Mar 29;277(13):11208-16. Epub 2002 Jan 15. | http://www.ncbi.nlm.nih.gov/pubmed/11792701 PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0053183 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
0.31-0.63 μM
MIC
PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0066013 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cationic peptide 04 (cupiennin); 01 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal
Pseudomonas aeruginosa
PMID11792701;10669026 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5