Peptide Database

Peptide NameHR1-1

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Anti-HIV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC178H291N51O63

DescriptionStandard

        NGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTA
    

Molecular Weight4153.52 Da

Isoelectric Point (pI)6.14

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0062

GRAVY Index-0.50

Hydrophobic Moment 0.71

Boman Index-0.01

Instability Index19.05

Aliphatic Index 84.74

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1922.72

LogP -26.72

H-bond Donors 63.0

H-bond Acceptors 63.0

Rotatable Bonds 143.0

Heavy Atoms 292.0

Ring Count 2.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418115 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetSARS-CoV(wild-type):inhibition of virus infection in 293T cells

Activity3.68 μM

MethodEC50

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