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MYP_065978
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Basic Information
Brevinin-2DYb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
33 amino acids
C145H250N40O42S2
Standard
Sequence
GLFDVVKGVLKGAGKNVAGSLLEQLKCKLSGGC
Physicochemical Analysis
3289.91 Da
9.24
2.74
2.50
0.0830
0.40
0.61
0.18
4.13
112.12
0.0303
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1325.86
-13.52
47.0
47.0
117.0
229.0
1.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0203874 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
Escherichia coli and Staphylococcus aureus
30 μM
MIC
PaperCytolytic peptides belonging to the brevinin-1 and brevinin-2 families isolated from the skin of the Japanese brown frog, Rana dybowskii
RECORD: Rec_0204142 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Brevinin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
PMID17688900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17688900/
RECORD: Rec_0231337 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
30 μM
MIC
PMID17688900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17688900/
RECORD: Rec_0271503 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0283752 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli
PMID17688900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17688900/
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