Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC377H613N109O103S7

DescriptionStandard

        MQRLVLLLAISLLFYQDLPVRSEFELDRICGYGTARCRKKCRSEEYKIGRCPNSYACCLRKWDEILLNRTKP
    

Molecular Weight8545.02 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)5.45

Net Charge (pH 7.4) 5.12

Charge Density (pH 7.0) 0.0757

GRAVY Index-0.31

Hydrophobic Moment 0.57

Boman Index-0.15

Instability Index59.41

Aliphatic Index 93.47

Aromaticity 0.0972

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3479.10

LogP -28.60

H-bond Donors 131.0

H-bond Acceptors 116.0

Rotatable Bonds 288.0

Heavy Atoms 596.0

Ring Count 11.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135464 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence