Peptide Database

Peptide NameCycloviolacin O7

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H202N30O38S6

DescriptionStandard

        SIPCGESCVFIPCISSIVGCSCKSKVCY
    

Molecular Weight2913.50 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.40

Net Charge (pH 7.4) 0.10

Charge Density (pH 7.0) 0.0143

GRAVY Index0.96

Hydrophobic Moment 0.37

Boman Index0.30

Instability Index24.76

Aliphatic Index 86.79

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1062.39

LogP -12.24

H-bond Donors 43.0

H-bond Acceptors 45.0

Rotatable Bonds 91.0

Heavy Atoms 198.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075816 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)