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MYP_065876
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Basic Information
HD5(1-13)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
13 amino acids
C56H96N22O18S3
Standard
Sequence
ATCYCRTGRCATR
Physicochemical Analysis
1461.69 Da
9.22
2.77
2.53
0.2127
-0.48
0.71
-0.38
2.70
15.38
0.0769
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
679.14
-10.44
30.0
24.0
45.0
99.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0074108 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PMID30808760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30808760/
RECORD: Rec_0167932 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 27853
>100 μM
MIC
PaperPaneth cell alpha-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
RECORD: Rec_0337989 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii 4-MRGN
100 μM
MIC
PMID30808760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30808760/
RECORD: Rec_0358932 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2020/144166 A1 Evidence URLhttps://patents.google.com/patent/WO2020144166A1/en PatentWO 2020/144166 A1
RECORD: Rec_0410017 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii 4-MRGN
>100 μM
MIC
PaperPaneth cell alpha-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments