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MYP_065855
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Basic Information
p369-CTL-A2xFVB
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C50H78N10O11
Standard
Sequence
KIFGSLAFL
Physicochemical Analysis
995.21 Da
8.75
0.76
0.55
0.0843
1.60
0.32
0.59
-0.54
141.11
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
342.37
-0.33
12.0
12.0
32.0
71.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0143215 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
N202.A2
10 %
Inhibition
PMID14991605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991605/
RECORD: Rec_0181168 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0223692 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
N202.A2
8 %
Inhibition
PMID14991605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991605/
RECORD: Rec_0225552 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
N202.A2
92 %
Inhibition
PMID14991605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991605/
RECORD: Rec_0254041 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
(Animals immunized three times with DC pulsed with p369-377 or p773-782 peptide showed ~25-30% tumor growth inhibition, while two immunizations induced ~12-15% tumor growth inhibition and one injection)
PaperPubMed PMID: 14991605 PMID14991605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14991605/
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