Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC916H1448N252O251S7

DescriptionStandard

        PTTPPMAHEPMLLLAVTEVVANSAAFTYFTAGALHRNISTLPRRFPFQLRTKSMEVFSPQLQERYPDQPMELHVWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGQPTITRNRLGGTVRLTGLVPNPELDGLSVLQVKRLETVLKFGLWLFGVPQANSKCCPRPVP
    

Molecular Weight20231.29 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)4.39

Net Charge (pH 7.4) 4.01

Charge Density (pH 7.0) 0.0240

GRAVY Index0.01

Hydrophobic Moment 0.82

Boman Index0.09

Instability Index52.04

Aliphatic Index 93.22

Aromaticity 0.0765

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7906.49

LogP -90.46

H-bond Donors 270.0

H-bond Acceptors 267.0

Rotatable Bonds 634.0

Heavy Atoms 1426.0

Ring Count 41.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219041 VERIFIED: NO

Provenance & Taxonomy

OrganismCatharus fuscescens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria