Peptide Database

Peptide NameRosA2 alpha

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC152H235N41O44S6

DescriptionStandard

        GSGVLGTLGCCSCLPWYSGWTVCGLACNPGKPCKN
    

Molecular Weight3533.13 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0485

GRAVY Index0.32

Hydrophobic Moment 0.41

Boman Index0.26

Instability Index31.01

Aliphatic Index 64.00

Aromaticity 0.0857

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1317.53

LogP -15.94

H-bond Donors 51.0

H-bond Acceptors 52.0

Rotatable Bonds 105.0

Heavy Atoms 243.0

Ring Count 8.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107769 VERIFIED: YES

Provenance & Taxonomy

OrganismS. roseosporus NRRL 11379 [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsTTWACATVTLTVTVCSPTGTLCGSCSMGTRGCC. Both peptides together exhibit antimicrobial activity against L. monocytogenes MTCC 839, B. subtilis MTCC 121 and E. coli MTCC 1610

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetBacillus subtilis MTCC 121