Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC544H869N145O168S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKGSGRSTVYISKVSVTAVFSTPLDNTGHTSISLTSCQTTSGDIDIKLNGKN
    

Molecular Weight12224.78 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.02

Hydrophobic Moment 0.53

Boman Index0.14

Instability Index12.31

Aliphatic Index 92.28

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5023.85

LogP -58.53

H-bond Donors 179.0

H-bond Acceptors 176.0

Rotatable Bonds 403.0

Heavy Atoms 860.0

Ring Count 17.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390206 VERIFIED: NO

Provenance & Taxonomy

OrganismCeuthmochares aereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria