Peptide Database

Peptide Name[His5]PTH-(1-34) (human)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC181H287N57O51S2

DescriptionStandard

        SVSEHQLMHNLGKHLNSMERVEWLRKKLQDVHNF
    

Molecular Weight4141.70 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)0.82

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0240

GRAVY Index-0.90

Hydrophobic Moment 0.64

Boman Index-0.19

Instability Index54.64

Aliphatic Index 82.94

Aromaticity 0.0588

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1781.33

LogP -16.32

H-bond Donors 61.0

H-bond Acceptors 58.0

Rotatable Bonds 144.0

Heavy Atoms 291.0

Ring Count 7.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062542 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetPTH1 receptor (Rat); PTH1 receptor (Human); PTH2 receptor (Human)