Peptide Database

Peptide NameTemporin-1Sc (Temporin-SHc; Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC80H119N19O19

DescriptionStandard

        FLSHIAGFLSNLFGK
    

Molecular Weight1650.92 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0564

GRAVY Index0.87

Hydrophobic Moment 0.43

Boman Index0.44

Instability Index32.97

Aliphatic Index 110.67

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 608.97

LogP -3.66

H-bond Donors 21.0

H-bond Acceptors 21.0

Rotatable Bonds 53.0

Heavy Atoms 118.0

Ring Count 4.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363737 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetSaccharomyces cerevisiae

Activity10 μg/mL

MethodMIC

RECORD: Rec_0416127 VERIFIED: YES