Peptide Database

Peptide NameNN2211 (Glucagon- Like Peptide 1 Derivative)

Function Ontology

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Metabolic ▸ Glucose metabolism ▸ Antidiabetic ▸ Anti-diabetic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC151H228N42O47

DescriptionStandard

        HAEGTFTSDVSSYLEGQAAKEFIAWLVRGRG
    

Molecular Weight3383.68 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.0369

GRAVY Index-0.25

Hydrophobic Moment 0.57

Boman Index0.06

Instability Index15.64

Aliphatic Index 69.35

Aromaticity 0.1290

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1444.28

LogP -15.15

H-bond Donors 52.0

H-bond Acceptors 47.0

Rotatable Bonds 110.0

Heavy Atoms 240.0

Ring Count 6.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272352 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGLP-1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Modsγ-Glu-palmitoyl residue at position 21

Bio-Activity Profile

Function

Anti-diabetic

Half-LifeSubcutaneously injected in Humans, in vivo; 39600 s

RECORD: Rec_0343028 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; synthetic construct [Synthetic]

FamilyGLP-1

Tax ID9606;32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSide-chain acyl/linker conjugation

Bio-Activity Profile

Function

Antidiabetic GLP-1 receptor agonist Weight management

TargetHuman GLP-1 receptor

Half-LifeClinical/Human: 13 h