Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC770H1236N206O237S14

DescriptionStandard

        MNLLILTFIICGLLTQVTKGSFEPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISYEYTRRPPFRVIHPEDITFDYSDMGSFTGSPVSKLSDLVTFDARGETMTPKTNTPETTMPPSETTTSKTTMPSSKTTTSKTTMPPPSQMALTHN
    

Molecular Weight17620.20 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0296

GRAVY Index-0.36

Hydrophobic Moment 0.60

Boman Index-0.03

Instability Index64.77

Aliphatic Index 66.22

Aromaticity 0.0769

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7107.04

LogP -79.85

H-bond Donors 257.0

H-bond Acceptors 258.0

Rotatable Bonds 570.0

Heavy Atoms 1227.0

Ring Count 28.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334072 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence